Congenital anomaly due to failure of proper closure of neural tube.
Lumbosacral region is the commonest site
Risk Factors
● Folate and zinc deficiency
● Radiation exposure
● Alcoholism
● Overt diabetes mellitus
● Use of valproate and carbamazepine during pregnancy
Management:
● Prenatal diagnosis-AFP and acetyl cholinesterase estimation
● USG is the main modality used for NTD detection
● Early surgery along with VP shunt is used to prevent neurological deterioration.
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